In the film
Léon: The Professional, (Jean Reno, 1994), we see what many people think is a paintball hit.

Léon (Jean Reno) opens a leather case to reveal a scoped, suppressed rifle, which he assembles.
IMFDB calls it an
SGW Multimatch, an AR-15 style rifle.

Léon assembles the rifle, and instructs Mathilda (Natalie
Portman) on how to use it. When she asks who she should shoot, he simply
tells her "pick anyone".

Mathilda picks a jogger in Central Park, and manages to hit him with a
splat of red paint. The jogger turns out to be somebody important, who
is then mobbed and covered by his security team. It is
not, however, a paintball hit. Besides the fact the rifle cannot fire a conventional paintball,
the range would have been far too great anyway. What it could have been
however, was a Simunition, a non-lethal training round that can, in
fact,
be fired from (lightly altered) firearms, and shoots a frangible plastic shell that breaks on impact.